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Androgen receptors ARs play a critical role in the development of prostate cancer. Targeting ARs results in important salutary effects in this malignancy. This review describes patterns of AR expression in a spectrum of cancers, and the potential to exploit this knowledge in the clinical therapeutic setting.

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That is why anal play is much more acceptable today than it was a decade ago. A few years back, it was considered taboo, but today, both men and women are immersing themselves with fun stuff involving the bum. And, the adult toy industry has made the job so much easier.

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Please refresh the page and retry. NHS watchdogs have approved the new technique to treat one of the most common medical complaints facing older men. Around half of men over the age of 50 suffer from an enlarged prostatewhich can reduce bladder capacity, causing repeated night-time trips to the lavatory. Mild symptoms can be controlled by drugs, but they can cause side-effects such as loss of libido.

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Society is good at visually appreciating butts and writing catchy songs about butts, but still not so great at understanding how we might derive physical pleasure from our own butts—especially when it comes to the prostate. With that in mind, I asked Lewis and sex and relationships advisor Lianne Young to give some tips on how you can give your partner a prostate orgasm. Medically speaking, the prostate produces a fluid that mixes with sperm to create semen.

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This is evidenced by an increased enthusiasm for all this ass among the hoi polloi and the increasing sales and use of prostate massagers. The rest is largely sperm and seminal vesicle fluid and these ingredients mix during orgasm. That spasm you feel when you ejaculate?

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They secrete a fluid that helps lubricate the urethral opening, and are surrounded with tissue that swells with blood during sexual arousal. The Skene's glands are located in the general area of the vulvaon the anterior wall of the vagina around the lower end of the urethra. The Skene's glands are homologous with the prostate gland in males, containing numerous microanatomical structures in common with the prostate gland, such as secretory cells.

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Over the last year several of my clients have shown curiosity about prostate massages, apparently a new hot trend in male sexuality, whether heterosexual, bisexual or homosexual. Several health professionals are recommending prostate massage as a preventive health practice, and some men are reporting it gives them the best orgasms they have ever experienced. In some Asian countries, prostate massage therapy is widely practised by men to enhance their sexual performance.

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A Man and His Prostate. Playing the part of 'The Man' tonight -- Ed Asner! You may expect a one-man play starring showbiz icon Ed Asner to be an autobiographical piece about the actor's life and decades-spanning career in the entertainment world.

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